Recent Publications

Hess NJ, Hudson AW, Hematti P, Gumperz JE.  Early T Cell Activation Metrics Predict Graft-versus-Host Disease in a Humanized Mouse Model of Hematopoietic Stem Cell Transplantation.  Journal of Immunology 2020 Jul 1;205(1):272-281. 

Zumwalde NA, Gumperz JE. 2020. Mucosal-Associated Invariant T Cells in Tumors of Epithelial Origin. (In: Tumor Microenvironment. Advances in Experimental Medicine and Biology, vol 1224. Ed Birbrair A. Springer, Nature) 

Sharma A, Zumwalde NA, Gumperz JE.  Expansion and Adoptive Transfer of Human Vδ2+ T cells to Assess Antitumor Effects In Vivo.  2019;1884:57-72  (In Methods in Molecular Biology, Cancer Immunosurveillance.  Eds Lopez-Soto A, and Folgueras AR.  Springer Nature). 

Zumwalde NA, Haag JD, Gould MN, Gumperz JE. Mucosal associated invariant T cells from human breast ducts mediate a Th17-skewed response to bacterially exposed breast carcinoma cells. Breast Cancer Research 2018; Sep 12;20(1):111 

Sharma A, Lawry SM, Klein BS, Wang X, Sherer NM, Zumwalde NA, Gumperz JE. LFA-1 ligation by high-density ICAM-1 is sufficient to activate IFN-γ release by innate T lymphocytesJournal of Immunology 2018; Oct 15;201(8):2452-61. 

Zumwalde NA, Gumperz JE.  Modeling Human Antitumor Responses In Vivo Using Umbilical Cord Blood-Engrafted Mice.  Frontiers in Immunology 2018; Jan 26;9:54. 

Zumwalde NA, Sharma A, Xu X, Ma S, Schneider C, Romero-Masters JC, Hudson AW, Gendron-Fitzpatrick A, Kenney SC, Gumperz JE. Adoptively transferred Vγ9Vδ2 T cells with low PD-1 expression show potent anti-tumor effects in a pre-clinical model of human B cell lymphomagenesis.  JCI Insight 2017; Jul 6;2(13). pii: 93179. 

Xu X,Pocock GM, Sharma A, Peery SL. Fites JS, Felley L, Zarnowski R, Stewart D, Berthier E, Klein BS, Sherer NM, Gumperz JE. Human iNKT cells promote protective inflammation by inducing oscillating purinergic signaling in monocyte-derived DCs. Cell Reports 2016; Sep 20;16(12):3273-85. 

Felley LE, Gumperz JE. Are human iNKT cells keeping tabs on lipidome perturbations triggered by oxidative stress in the blood? Immunogenetics  2016; Aug;68(8):611-22. 

Felley LE, Sharma A, Theisen E, Romero-Masters JC, Sauer J-D, Gumperz JE. Human Invariant NKT Cells Induce IL-1β Secretion by Peripheral Blood Monocytes via a P2X7-Independent Pathway. Journal of Immunology 2016; Sep 15;197(6):2455-64. 

Zumwalde NA, Haag JD, Sharma D, Mirrielees JA, Wilke LG, Gould MN, Gumperz JE. Analysis of immune cells from human mammary ductal epithelium reveals Vδ2+T cells that efficiently target breast carcinoma cells in the presence of bisphosphonate. Cancer Prevention Research 2016; Jan 25 Apr;9(4):305-16.